
- Perindopril is a medicine that belongs to a class of medications known as “angiotensin converting enzyme (ACE) inhibitor”.
- Amlodipine belongs to a class of medicines known as” calcium channel blockers”.
- One tablet of this product replaces two separate products of Perindopril and Amlodipine.
- This combination of active ingredients acts by widening the blood vessels making it easier for your heart to pump blood through them. This medicine is used for the following indications:
- to treat hypertension (high blood pressure).
- to decrease the risk of cardiac events, like heart attack, in patients with coronary artery disease.
Do not take Perindopril/ Amlodipine:
- If you have an allergy to perindopril, or amlodipine, or any of the other ingredients of this medicine, or to any other ACE inhibitor or calcium channel blocker.
- If you have previously experienced angioedema to perindopril or another ACE inhibitor.
- Angioedema is a condition that is manifested by signs and symptoms like swelling of the face, throat or tongue, wheezing, intense itching or severe skin rashes.
- If a family member has previously experienced angioedema to perindopril or another ACE inhibitor.
- If you are being treated with sacubitril/valsartan (used for heart failure).
- If you are pregnant or plan to become pregnant.
- If you have diabetes mellitus or kidney problems and you are taking aliskiren.
- If you have renal artery stenosis (artery supplying blood to the kidney becomes narrow).
- If you have aortic stenosis (main blood vessel that leads to the heart becomes narrowed).
- If you have severe low blood pressure.
- If you have unstable angina (pain or discomfort in the chest that lasts for more than a few minutes or happens at rest and may not be decreased with medication).
- If you have cardiogenic shock (a severe and sudden decrease in blood flow and blood pressure through the body because of poor pumping of the heart muscle).
- If you have heart failure (heart muscle is not able to pump blood properly to the body) within the first 28 days following a heart attack.