• The active ingredient of this drug called Metformin.


• Metformin XR Extended-Release Tablets are oral antihyperglycemic drugs used in the management of type 2 diabetes.


• It controls blood sugar (glucose) and helps your body use insulin effectively.


• This medication is often combined with changes to diet and exercise.


• This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

How To Use:

• There is no fixed dosage regimen for the management of hyperglycemia in patients with type 2 diabetes with METFORMIN XR .


• Dosage of METFORMIN XR must be individualized on the basis of both effectiveness and tolerance, while not exceeding the maximum recommended daily doses.


• The maximum recommended daily dose of METFORMIN XR in adults is 2000 mg.


• METFORMIN XR should generally be given once daily with the evening meal.


• METFORMIN XR should be started at a low dose, with gradual dose escalation, both to reduce gastrointestinal side effects and to permit identification of the minimum dose required for adequate glycemic control of the patient.

Adults:

• The usual starting dose of METFORMIN XR (metformin hydrochloride) Extended-Release Tablets is 500 mg once daily with the evening meal.


• Dosage increases should be made in increments of 500 mg weekly, up to a maximum of 2000 mg once daily with the evening meal.


• If glycemic control is not achieved on METFORMIN XR 2000 mg once daily, a trial of METFORMIN XR  1000 mg twice daily should be considered.


• If higher doses of metformin are required, METFORMIN should be used at total daily doses up to 2550 mg administered in divided daily doses, as described above.